Apolipoprotein E, but Not Apolipoprotein B, Is Essential for Efficient Cell-to-Cell Transmission of Hepatitis C Virus
نویسندگان
چکیده
منابع مشابه
Apolipoprotein E but not B is required for the formation of infectious hepatitis C virus particles.
Our previous studies have found that hepatitis C virus (HCV) particles are enriched in apolipoprotein E (apoE) and that apoE is required for HCV infectivity and production. Studies by others, however, suggested that both microsomal transfer protein (MTP) and apoB are important for HCV production. To define the roles of apoB and apoE in the HCV life cycle, we developed a single-cycle HCV growth ...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2015
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.00577-15